Shire – SCPCD

Differential Diagnosis Desktop 400X240

Differential Diagnosis

Purpura fulminans:
Is it acquired or congenital protein C deficiency?

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Purpura Fulminans - Investigation

Key learnings for the management of purpura fulminans: is it congenital or acquired protein C deficiency?

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How to test
for SCPCD?

There are several recommended tests that can help you determine whether your patient has SCPCD.

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Options for
management
of SCPCD

Treatments include protein C replacement, anti-coagulation and liver transplantation.⁵

References:

Chalmers E, et al. Purpura fulminans: recognition, diagnosis and management. Archives of Disease in Childhood. 2011;96(11):1066-1071.
Price VE, et al. Diagnosis and management of neonatal purpura fulminans. Semin Fetal Neonatal Med. 2011;16(6):318-22.
Goldenberg N, Manco-Johnson M. Protein C deficiency. Haemophilia. 2008;14(6):1214–1221.
Marlar RA, et al. Report on the diagnosis and treatment of homozygous protein C deficiency. Report of the Working Party on Homozygous Protein C Deficiency of the ICTH-Subcommittee on Protein C and Protein S. Thromb Haemost. 1989;61(3):529-31.
Kroiss S, Albisetti M. Use of human protein C concentrates in the treatment of patients with severe congenital protein C deficiency. Biologics: Targets & Therapy. 2010;4:51–60.

C-ANPROM /INT/ /5460- November 2019

PURPURA FULMINANS INVESTIGATION

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